Aside from flow, what is another major factor in determining cannula selection?

The selection of cannulas for ECMO is critically influenced by multiple factors, with one of the major considerations being the pressure drop across the cannula. The pressure drop refers to the change in pressure that occurs as blood flows through the cannula, which can affect the overall efficiency and effectiveness of blood flow during ECMO. A significant pressure drop may limit blood flow and increase the workload on the pump, which can compromise patient outcomes.

Understanding the pressure drop is essential for optimal cannula choice, as it directly correlates with the flow rates that can be achieved, the needs of the patient, and the characteristics of the ECMO circuit. Selecting a cannula that minimizes pressure drop while maximizing blood flow can enhance the performance of the ECMO support, ensuring that adequate perfusion and oxygenation are maintained throughout the patient's treatment.

In contrast, factors such as blood pH, oxygenation level, and temperature have their own importance in the broader context of patient management and ECMO support, but they do not play a direct role in the physical selection of the cannula itself as pressure drop does.