Which of the following is NOT a method to minimize oxygen consumption?

Increasing physical activity is indeed not a method to minimize oxygen consumption. In fact, physical activity generally raises metabolic demand and thus increases oxygen consumption in the body. When a patient is in a critical condition, such as when ECMO is being considered, reducing oxygen consumption is crucial to enhance the efficiency of oxygen delivery and to ensure that vital organs receive adequate oxygen without excessive stress on the body.

On the other hand, the other options provided are common strategies utilized to lower oxygen consumption. Increasing sedatives can decrease a patient's metabolic rate by inducing a state of sedation, thereby reducing overall activity and oxygen demand. Inducing hypothermia is another effective way to lower metabolic rates, as decreased body temperature leads to a reduction in metabolic processes, thus conserving oxygen. Treating infection is also vital since infections can lead to increased metabolic demands as the body fights off pathogens; resolving an infection can help to normalize these demands.

In summary, engaging in physical activity would counteract the goal of minimizing oxygen consumption, making it the exception among the strategies listed.